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Welcome

The Reineke Lab is part of the Department of Pharmaceutical Sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University.

Nanoparticle drug delivery systems provide protection and enhanced uptake of therapeutic agents allowing efficient, non-parenteral drug delivery with targeted and sustained release potential. We are interested in the use of polymeric nanoparticles as drug carriers for
delivery via the pulmonary route. However, cellular and molecular mechanisms of nanoparticle uptake, transit, organ distribution and elimination (ADME) are poorly understood. Projects focus on the mechanisms involved in ADME of nanoparticles and biodistribution profile analysis for rational design of nanoparticles for organ- and/or pathology-directed therapies.

4/28/10 Dr. Tamara Minko, Rutgers University, presents seminar: "Nanotechnology Strategies to Overcome Limitations in Cancer Chemotherapy."

4/25/10 Undergraduate Josephine Cheng wins competitive Undergraduate Research Award to work in Reineke Lab in summer/fall 2010.

4/5/10: Undergraduate Josephine Cheng wins competitive fellowship (SURF) to work in Reineke lab Summer 2010.

3/28/10: Abdul Khader Mohammad is awarded 2nd prize for his poster, "Pulmonary Nanoparticle Internalization and Transit Pathways" at the WSU Graduate Exhibition.

2/16/10: Dr. Justin Hanes, Johns Hopkins University, presents seminar.

2/8/10: Nanotechnology-Based Biomarker Detection (J. Reineke) in the book, Biomarkers in Drug Development published.

12/16/09: Dr. Glen Kwon, Professor, University of Wisconsin-Madison presents seminar.

12/2/09: Steve Schwendeman, PhD, associate professor of Pharmaceutical Sciences, University of Michigan, presents "Creating new PLGA systems for delivery of peptides and proteins."

7/18/09: Reineke Lab has 3 poster presentations at the Controlled Release Society Annual Meeting in Copenhagen, Denmark.

3/1/09: Reineke Lab is awarded the EACPHS Faculty Research Award Program FRAP) Young Investigator Award for work entitled, "Functional Genomic Response of Alveolar Cells to Nanoparticles."
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